BioJapan 2023German Exhibitors YUMAB GmbH
YUMAB GmbH

YUMAB GmbH

Booth number: C-18-2
www.yumab.com

About us

YUMAB is a biotechnology company founded in 2012 and has become a world leading provider for the development of fully human, therapeutic antibodies.

YUMAB offers outstanding expertise from more than 30 years of continuous research in recombinant antibody technologies in combination with state of the art and next generation technologies. This unique setting enables novel solutions for current and future challenges in antibody immunotherapy.

The success of next generation antibody drug development relies on comprehensive discovery technologies and strategies.

YUMAB bridges the gap between research innovation and novel therapies. Our advanced discovery platform provides access to challenging targets, enables new formats, and accelerates the development of human antibodies at a high success rate.

From target discovery to fully characterized lead – our experienced team leads biotech and pharma teams worldwide through the development process as your trusted, de-risking partner.

YUMAB 2023 (© Land Niedersachsen-Lars Kaletta)

YUMAB 2023 (© Land Niedersachsen-Lars Kaletta)

YUMAB 2023 (© Land Niedersachsen-Lars Kaletta)

YUMAB 2023 (© Land Niedersachsen-Lars Kaletta)

YUMAB 2023 (© Land Niedersachsen-Lars Kaletta)

Address

YUMAB GmbH
Inhoffenstr. 7
38124 Braunschweig
Germany

Phone:  +49 5314 811700

Contact person:

Alexander Ehm
Head of Commercial Management
E-mail: a.ehm@yumab.com
Phone: +49 1702 800357

Products & Services

  1. Fast track discovery of fully human antibodies
  2. Immune or patient derived libraries (also from transgenic animals)
  3. Antibody lead development (IgG, Fab, scFv, bispecifics, CAR, ADC, ...)
  4. Antibody engineering (affinity, stability, manufacturability)
  5. In silico lead optimization
  6. Hybridoma sequencing
  7. Humanization, Superhumanization
  8. Contract research and development
  9. Partnered development

YUMAB® Antibody Discovery

YUMAB’s advanced in-vitro antibody generation pipeline employs phage display selection in combination with our proprietary universal naïve human antibody gene libraries or customized immune libraries.
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YUMAB® Antibody Discovery

YUMAB® Antibody Engineering

The YUMAB® platform can be used for the engineering of already existing antibodies that were generated externally. Two in-vitro evolution technologies are available for the optimization of the antibody’s affinity, stability, specificity or selectivity:
- in-vitro evolution by YUlight shuffling
- in-vitro evolution by mutagenesis
Additionally, in-silico analysis can be applied to identify and optimize antibodies with the best developability score.
- in-silico analysis and optimization
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YUMAB® Antibody Engineering

YUMAB® Antibody Humanization

The YUMAB® humanization platform provides two technologies for the humanization of animal-derived antibodies of any source (B-cells, Hybridoma cultures, antibody sequences) by:

- Germline-optimized CDR grafting
- Template-driven chain shuffling
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YUMAB® Antibody Humanization

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